Douglas M. Fambrough, Ph.D.
General Partner
Boston, MA
dfambrough@oxbio.com
Since joining Oxford in 1999, Dr. Fambrough has specialized in financing innovative life science technology companies. His current projects include Dicerna Pharmaceuticals, a second generation “RNA Interference” company co-founded by Dr. Fambrough; Cambrios Technologies, which invented and now markets biologically-inspired electronic materials for touch screens, flat panel displays, and photovoltaics; Xencor, a protein engineering company that engineers antibody Fc regions to enhance drug potency; Rib-X Pharmaceuticals, a developer of antibiotics against multi-drug resistant pathogens; and Solstice Neurosciences, which markets the protein drug Myobloc for movement disorders. His past investments include RNA Interference pioneer Sirna Therapeutics, acquired by Merck for $1.1 billion, and the ultra-high-throughput DNA sequencing equipment company Solexa, acquired by Illumina for $600 million. Prior to Oxford, Dr. Fambrough was a genomic scientist at the Whitehead/MIT Center for Genome Research (now known as the Broad Institute). He graduated from Cornell University and obtained his Ph.D. in genetics from the University of California, Berkeley.







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